東京健康長(zhǎng)壽醫(yī)學(xué)研究所大澤郁朗教授Ikuroh Ohsawa, Tokyo MetropolitanInstitute of Gerontology
大澤郁朗是2007年在《自然醫(yī)學(xué)》雜志發(fā)表氫分子生物學(xué)里程碑論文的第一作者，當(dāng)時(shí)他在日本醫(yī)學(xué)大學(xué)老年病研究所太田成男教授課題組，氫分子領(lǐng)域10數(shù)篇關(guān)鍵論文都是他作為作者完成，后來(lái)關(guān)于動(dòng)脈硬化的保護(hù)效應(yīng)的論文他仍作為第一作者，最近他的課題組發(fā)表用于精子保護(hù)效應(yīng)的研究。
1. Nakata K, Yamashita N, Noda Y, Ohsawa I.Stimulation of human damagedsperm motility with hydrogen molecule. Med Gas Res. 2015 Jan 10;5(1):2.
2. Iio A, Ito M, Itoh T, Terazawa R, Fujita Y, Nozawa Y, Ohsawa I, OhnoK, Ito M. Molecular hydrogen attenuates fatty acid uptake and lipidaccumulation through downregulating CD36 expression in HepG2 cells. Med GasRes. 2013 Mar 1;3(1):6.
3. Terasaki Y, Ohsawa I, Terasaki M, Takahashi M, Kunugi S, Dedong K,Urushiyama H, Amenomori S, Kaneko-Togashi M, Kuwahara N, Ishikawa A, KamimuraN, Ohta S, Fukuda Y. Hydrogen therapy attenuates irradiation-induced lungdamage by reducing oxidative stress. Am J Physiol Lung Cell Mol Physiol. 2011Oct;301(4):L415-26.
4. Kamimura N, Nishimaki K, Ohsawa I, Ohta S. Molecular hydrogen improvesobesity and diabetes by inducing hepatic FGF21 and stimulating energymetabolism in db/db mice. Obesity (Silver Spring). 2011 Jul;19(7):1396-403.
5. Oharazawa H, Igarashi T, Yokota T, Fujii H, Suzuki H, Machide M,Takahashi H, Ohta S, Ohsawa I. Protection of the retina by rapid diffusion ofhydrogen: administration of hydrogen-loaded eye drops in retinal ischemia-reperfusioninjury. Invest Ophthalmol Vis Sci. 2010 Jan;51(1):487-92.
6. Suzuki Y, Sano M, Hayashida K, Ohsawa I, Ohta S, Fukuda K. .Are theeffects of alpha-glucosidase inhibitors on cardiovascular events related toelevated levels of hydrogen gas in the gastrointestinal tract? FEBS Lett. 2009Jul 7;583(13):2157-9.
7. Fu Y, Ito M, Fujita Y, Ito M, Ichihara M, Masuda A, Suzuki Y, MaesawaS, Kajita Y, Hirayama M, Ohsawa I, Ohta S, Ohno K. Molecular hydrogen isprotective against 6-hydroxydopamine-induced nigrostriatal degeneration in arat model of Parkinson's disease. Neurosci Lett. 2009 Apr 3;453(2):81-5.
8. Nakashima-Kamimura N, Mori T, Ohsawa I, Asoh S, Ohta S. Molecularhydrogen alleviates nephrotoxicity induced by an anti-cancer drug cisplatinwithout compromising anti-tumor activity in mice. Cancer Chemother Pharmacol.2009 Sep;64(4):753-61.
9. Ohsawa I, Nishimaki K, Yamagata K, Ishikawa M, Ohta S. Consumption ofhydrogen water prevents atherosclerosis in apolipoprotein E knockout mice.Biochem Biophys Res Commun. 2008 Dec 26;377(4):1195-8.
10.Nagata K, Nakashima-Kamimura N, Mikami T, Ohsawa I, Ohta S..Consumption of molecular hydrogen prevents the stress-induced impairments inhippocampus-dependent learning tasks during chronic physical restraint in mice.Neuropsychopharmacology. 2009 Jan;34(2):501-8.
11.Hayashida K, Sano M, Ohsawa I, Shinmura K, Tamaki K, Kimura K, Endo J,Katayama T, Kawamura A, Kohsaka S, Makino S, Ohta S, Ogawa S, Fukuda K..Inhalation of hydrogen gas reduces infarct size in the rat model of myocardialischemia-reperfusion injury. Biochem Biophys Res Commun. 2008 Aug15;373(1):30-5.
12.Fukuda K, Asoh S, Ishikawa M, Yamamoto Y, Ohsawa I, Ohta S. Inhalationof hydrogen gas suppresses hepatic injury caused by ischemia/reperfusionthrough reducing oxidative stress. Biochem Biophys Res Commun. 2007 Sep28;361(3):670-4.
13.Ohsawa I, Ishikawa M, Takahashi K, Watanabe M, Nishimaki K, YamagataK, Katsura K, Katayama Y, Asoh S, Ohta S. Hydrogen acts as a therapeutic antioxidantby selectively reducing cytotoxic oxygen radicals. Nat Med. 2007Jun;13(6):688-94. |
